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8625438 
Journal Article 
Microscale synthesis of phosphorus trichloride labeled with high specific activity 33p 
Woo, DV; Rupp, AF; Poggenburg, JK 
1978 
Yes 
Journal of Labelled Compounds and Radiopharmaceuticals
ISSN: 0362-4803
EISSN: 1099-1344 
JOHN WILEY & SONS LTD 
W SUSSEX 
15 
1 S 
117-125 
English 
WOS:A1978FW13500015 
Milligram quantities of high specific activity 33P‐labeled phosphorus trichloride are synthesized from carrier‐free 33P‐labeled phosphoric acid (33P‐H3PO4). Special apparatus were constructed for this synthesis. Carrierfree 33P‐H3PO4 is converted to lead phosphate in the presence of carrier by metathesis with lead oxide. Upon hydrogen reduction of the lead phosphate, elemental phosphorus is liberated and reacted with chlorine to form phosphorus pentachloride. Subsequent reduction in a specially constructed phosphorus reductor yields the phosphorus trichloride which is collected and sealed in an ampul. The procedures described are applicable to routine production of millicurie or multicurie quantities of several 33P‐labeled phosphorus intermediates. Copyright © 1978 John Wiley & Sons, Ltd. 
Phosphorus Pentachloride; Phosphorus Trichloride; Phosphorus‐33; Radio‐synthesis