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8641224 
Journal Article 
Genetic predisposition of hand-foot skin reaction after sorafenib therapy in patients with hepatocellular carcinoma 
Lee, JH; Chung, YH; Kim, JA; Shim, JH; Lee, D; Lee, HC; Shin, ES; Yoon, JH; Kim, BI; Bae, SH; Koh, KC; Park, NH 
2013 
Yes 
Cancer
ISSN: 0008-543X
EISSN: 1097-0142 
119 
1 
136-142 
22736425 
WOS:000312543000019 
Sorafenib currently sets the new standard for advanced hepatocellular carcinoma (HCC). It has been suggested that Asian patients with HCC have increased susceptibility to hand-foot skin reaction (HFSR) related to sorafenib therapy. The authors investigated the association between sorafenib-induced HFSR and genetic polymorphisms in Korean patients with HCC.