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8641683 
Journal Article 
Is green tea a potential trigger for autoimmune hepatitis? 
Gallo, E; Maggini, V; Berardi, M; Pugi, A; Notaro, R; Talini, G; Vannozzi, G; Bagnoli, S; Forte, P; Mugelli, A; Annese, V; Firenzuoli, F; Vannacci, A 
2013 
1 
Phytomedicine
ISSN: 0944-7113
EISSN: 1618-095X 
20 
13 
1186-1189 
English 
23928507 
WOS:000325445400006 
A case of autoimmune liver hepatitis is reported: the onset was triggered by consumption of green tea infusion in a patient taking oral contraceptives and irbesartan. We hypothesize that our patient, carrying genetic variant of hepatic metabolism making her particularly susceptible to oxidative stress, developed an abnormal response to a mild toxic insult, afforded by a combination of agents (oral contraceptives+irbesartan+green tea) that normally would not be able to cause damage. Her particular hepatic metabolism further increased the drugs' concentration, favoring the haptenization of liver proteins, eventually leading to the development of an autoimmune hepatitis.