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8656886 
Journal Article 
Bioactive Isoprenoid-Derived Natural Products from a Dongsha Atoll Soft Coral Sinularia erecta 
Huang, CY; Tseng, YJ; Chokkalingam, U; Hwang, TL; Hsu, CH; Dai, CF; Sung, PJ; Sheu, JH 
2016 
Yes 
Journal of Natural Products
ISSN: 0163-3864
EISSN: 1520-6025 
79 
5 
1339-1346 
English 
27142697 
WOS:000377150900015 
Four new isoprenoids, including two norcembranoids sinulerectols A and B (1 and 2), a cembranoid sinulerectol C (3), and a degraded cembranoid sinulerectadione (4), along with three known isoprenoids, an unnamed norcembrene (5), sinularectin (6), and ineleganolide (7), and a known nitrogen-containing compound (Z)-N-[2-(4-hydroxyphenyl)ethyl]-3-methyldodec-2-enamide (8), were isolated from an extract of the marine soft coral Sinularia erecta. The structure of sinularectin (6) was revised, too. Compounds 3, 4, and 8 exhibited inhibitory activity against the proliferation of a limited panel of cancer cell lines, whereas 1, 2, and 8 displayed potent anti-inflammatory activity in fMLP/CB-stimulated human neutrophils.