Health & Environmental Research Online (HERO)


Print Feedback Export to File
8657730 
Journal Article 
SMALL-MOLECULE ANTIOXIDANTS IN MARINE ORGANISMS - ANTIOXIDANT ACTIVITY OF MYCOSPORINE-GLYCINE 
Dunlap, WC; Yamamoto, Y 
1995 
Yes 
Comparative Biochemistry and Physiology - Part B: Biochemistry and Molecular Biology
ISSN: 1096-4959
EISSN: 1879-1107 
112 
1 
105-114 
WOS:A1995RT84300012 
The antioxidant activities of aqueous extracts of tissues from four different marine species containing mycosporine-like amino acids were examined by their peroxyl radical-trapping abilities using the phosphatidylcholine peroxidation inhibition assay, The coral trout (Plectropomus leopardus) lens extract had low oxidation inhibition activity; Porphyra tenera and Lissoclinum patella extracts had moderately strong inhibition activities while the aqueous extract of Palythoa tuberculosa showed the greatest oxidation inhibition activity of the extracts tested; the last two extracts contained mycosporine-glycine. In these sample extracts, mycosporine-glycine was reactive to peroxyl radicals whereas the iminomycosporine-like amino acids, shinorine, porphyra-334, palythine, asterina-330 and palythinol, were oxidatively robust. Purified mycosporine-glycine inhibited peroxyl radical-initiated autoxidation of phosphaditylcholine in a concentration-dependent manner. These results suggest that mycosporine-glycine may function as a biological antioxidant in marine organisms. 
ANTIOXIDANTS; CORAL TROUT; LISSOCLINUM PATELLA; MYCOSPORINE-LIKE AMINO ACIDS; MYCOSPORINE-GLYCINE; OXIDATIVE STRESS; PALYTHOA TUBERCULOSA; PORPHYRA TENERA