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8685548 
Journal Article 
Aromatization of hexahydrobenzoic acid by mammalian liver mitochondria 
Mitoma, C; Posner, HS; Leonard, F 
1958 
1 
Biochimica et Biophysica Acta
ISSN: 0006-3002
EISSN: 1878-2434 
27 
C 
156-160 
English 
1. 1. The enzyme system which aromatizes cyclohexanecarboxylic acid has been shown to be localized in the mitochondrial fraction of guinea pig liver. 2. 2. The sequence of reactions has been shown to be the formation of the CoA derivative of the acid, dehydrogenation and the conjugation with glycine to form hippuric acid. 3. 3. The removal of the oxidation product, benzoic acid, as hippuric acid greatly accelerated the oxidation reaction. 4. 4. Analogy between the present system and the fatty acid oxidase system has been discussed. 1958.