Effect of the hypocholesterolemic drug AY9944 on developing central nervous system of rats: Alteration of endoplasmic reticulum in oligodendroglia | Health & Environmental Research Online (HERO)

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Citation
Tags

HERO ID

8703599

Reference Type

Journal Article

Title

Effect of the hypocholesterolemic drug AY9944 on developing central nervous system of rats: Alteration of endoplasmic reticulum in oligodendroglia

Author(s)

Suzuki, K; Zagoren, JC

Year

1973

Is Peer Reviewed?

Yes

Journal

Journal of Neurocytology
ISSN: 0300-4864
EISSN: 1573-7381

Volume

Issue

Page Numbers

369-381

Language

English

DOI

10.1007/BF01103795

Abstract

Unusual alterations of the endoplasmic reticulum were seen in the oligodendroglia of young rats treated with AY9944. They consisted of: 1. random proliferation of membranes within the cytoplasm, some of them with attached ribosomes; 2. multi-layers of paired membranes connected to the cisternae of the rough endoplasmic reticulum which encircled the cytoplasm of oligodendroglia as a whole or focally; 3. formation of numerous small whorls of about 0.5 μm in diameter which are made up of two fused membranes of the rough endoplasmic reticulum. 1973 Chapman and Hall Ltd.