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8703801 
Journal Article 
Selection of a reference partitioning system for drug design work 
Smith, RN; Hansch, C; Ames, MM 
1975 
Yes 
Journal of Pharmaceutical Sciences
ISSN: 0022-3549
EISSN: 1520-6017 
64 
4 
599-606 
English 
Consideration of the structural, polar, and transport properties of water‐saturated solvent and solvent‐saturated water phases of three general and eight specific binary systems leads to the conclusion that the n‐octanol—water system is a very good allround compromise for use as a reference system for biological partitioning in drug design work. Copyright 1975 Wiley‐Liss, Inc., A Wiley Company 
Biological partitioning—reference systems, structural, polar, and transport properties of solvent and water phases; Partitioning systems—selection of a reference for drug design work, structural, polar, and transport properties of solvent and water phases, n‐octanol—water system and others; Transport—selection of a reference partitioning system for drug design work