The inhibiting effects of Urtica dioica root extracts on experimentally induced prostatic hyperplasia in the mouse | Health & Environmental Research Online (HERO)

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Citation
Tags

HERO ID

8708786

Reference Type

Journal Article

Title

The inhibiting effects of Urtica dioica root extracts on experimentally induced prostatic hyperplasia in the mouse

Author(s)

Lichius, JJ; Muth, C

Year

1997

Is Peer Reviewed?

Journal

Planta Medica
ISSN: 0032-0943
EISSN: 1439-0221

Volume

Issue

Page Numbers

307-310

Language

English

PMID

9270373

DOI

10.1055/s-2006-957688

Abstract

Extracts of stinging nettle roots (Urtica dioica L., Urticaceae) are used in the treatment of benign prostatic hyperplasia (BPH). We established a BPH-model by directly implanting an urogenital sinus (UGS) into the ventral prostate gland of an adult mouse. Five differently prepared stinging nettle root extracts were tested in this model. The 20% methanolic extract was the most effective with a 51.4% inhibition of induced growth.

Keywords

3β-sitosterin; benign prostatic hyperplasia (BPH); polysaccharides; scopoletin; Urtica dioica agglutinin (UDA); Urtica dioica L.; Urticaceae