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HERO ID
8713894
Reference Type
Journal Article
Title
Tuning the reactivity of glycosides: Efficient one-pot oligosaccharide synthesis
Author(s)
Grice, P; Ley, SV; Pietruszka, J; Priepke, HWM; Walther, EPE
Year
1995
Is Peer Reviewed?
1
Journal
Synlett
ISSN:
0936-5214
EISSN:
1437-2096
Volume
1995
Issue
7
Page Numbers
781-784
Language
English
DOI
10.1055/s-1995-5052
Abstract
Tuning the reactivity of glycosyl donors by selective introduction of different protecting and leaving groups enabled highly efficient oligosaccharide synthesis. Utilising both phenylseleno and ethylthio glycosides in combination with the cyclohexane-1,2-diacetal (CDA) protecting group provided four different levels of reactivity. One-pot sequential glycosidation of three components gave trisaccharides and tetrasaccharides. 1995 Georg Thieme Verlag, Rudigerstr. 14, 70469 Stuttgart, Germany. All rights reserved.
Keywords
cyclohexane-1,2-diacetals (CDA); oligosaccharides; one-pot synthesis; Reactivity tuning
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