Health & Environmental Research Online (HERO)


Print Feedback Export to File
8721442 
Journal Article 
In vitro study to investigate the antimicrobial efficacy of different toothpastes and mouth rinses 
Gibraiel, F; Rajput, M; Rajput, MS; Singh, M; Saxena, N; Vishal, A; Jha, AK 
2014 
0 
Research Journal of Pharmaceutical, Biological and Chemical Sciences
ISSN: 0975-8585 
5 
2 
245-257 
English 
The aim of the present in vitro study was to investigate the antimicrobial efficacy of different dentifrices (toothpastes and mouth rinses) and to study the variations in their effectiveness against the test microorganisms. Escherichia coli and Candida albicans were selected as test microorganisms against which the different toothpastes and mouth rinses were tested. The procedure included the evaluation of dentifrices, antimicrobial assay by modified agar well diffusion method and finally statistical analysis. This investigation showed that toothpaste having natural formulation gave maximum zones of inhibition against Candida albicans at all dilutions and E. coli at 1:1 dilution. Results from our study have shown that toothpaste formulation containing natural antimicrobial agents were more effective in controlling the oral microflora compared to toothpastes containing synthetic antimicrobial agents. 
Candida albicans; Escherichia coli; Natural antimicrobial agents; Toothpastes and mouth rinses; Zone of inhibition