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HERO ID
8728395
Reference Type
Journal Article
Subtype
Review
Title
Chemoautotroph Cupriavidus necator as a potential game-changer for global warming and plastic waste problem: A review
Author(s)
Sohn, YJ; Son, J; Jo, SY; Park, SY; Yoo, JI; Baritugo, KA; Na, JG; Choi, JI; Kim, HT; Joo, JC; Park, SJ
Year
2021
Is Peer Reviewed?
Yes
Journal
Bioresource Technology
ISSN:
0960-8524
EISSN:
1873-2976
Volume
340
Page Numbers
125693
Language
English
PMID
34365298
DOI
10.1016/j.biortech.2021.125693
Abstract
Cupriavidus necator, a versatile microorganism found in both soil and water, can have both heterotrophic and lithoautotrophic metabolisms depending on environmental conditions. C. necator has been extensively examined for producing Polyhydroxyalkanoates (PHAs), the promising polyester alternatives to petroleum-based synthetic polymers because it has a superior ability for accumulating a considerable amount of PHAs from renewable resources. The development of metabolically engineered C. necator strains has led to their application for synthesizing biopolymers, biofuels and biochemicals such as ethanol, isobutanol and higher alcohols. Bio-based processes of recombinant C. necator have made much progress in production of these high-value products from biomass wastes, plastic wastes and even waste gases. In this review, we discuss the potential of C. necator as promising platform host strains that provide a great opportunity for developing a waste-based circular bioeconomy.
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