Health & Environmental Research Online (HERO)

Print Feedback Export to File
Journal Article 
Chemical constituents of mangrove plant Aegiceras corniculatum 
Wang, JD; Dong, ML; Zhang, W; Shen, X; Guo, YW 
Zhongguo Tianran Yaowu
ISSN: 1672-3651 
China Pharmaceutical University 
Aim: To study the chemical constituents of mangrove plant Aegiceras corniculatum, aiming at searching for new bioactive substances. Method: The EtOAc extract of Aegiceras corniculatum was subjected to repeated silica gel and Sephadex LH-20 column chromatography to afford nine compounds. The structures were elucidated on the basis of spectroscopic analysis. Results: Nine compounds were isolated and identified as falcarindiol (1), p-hydroxyphenethyl anisate (2), phthalic acid, bis (2-ethylhexyl) ester (3), 1-hentriacontanol (4), resveratrol (5), 1,5-dihydroxy-3-methoxy-7-methylanthraquinone (6), 1,3,5-trihydroxy-7-methylanthraquinone (7), quercetin (8) and lupeol (9). Conclusion: All the compounds were isolated from the plant for the first time. Compound 1 shows inhibitory activity towards PTP1B with the IC50 value of 9.15 ± 2.48 μmol·L-1. 
Aegiceras corniculatum; Chemical constituents; Mangroves; 1 hentriacontanol; 1,3,5 trihydroxy 7 methylanthraquinone; 1,5 dihydroxy 3 methoxy 7 methylanthraquinone; 4 hydroxyphenethyl anisate; Aegiceras corniculatum extract; bis(2 ethylhexyl)ester phthalic acid; falcarindiol; lupeol; plant extract; plant medicinal product; protein tyrosine phosphatase 1B; quercetin; resveratrol; sephadex; silica gel; unclassified drug; aegiceras corniculatum; article; chemical composition; column chromatography; drug activity; drug identification; drug isolation; drug structure; enzyme inhibition; IC 50; mangrove; medicinal plant; nonhuman; spectroscopy