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9559474 
Journal Article 
Determination of amoxicillin in pharmaceutical preparations by molecularly imprinted polymer in polyvinyl chloride matrix membrane 
Hussein, HJ; Al-Bayati, YK 
2021 
International Journal of Drug Delivery Technology
ISSN: 0975-4415 
Dr. Yashwant Research Labs Pvt. Ltd. 
11 
1 
232-237 
English 
This study was based on synthesizing four electrodes based on molecularly imprinted polymers (MIPs). Using amoxicillin sodium (AMX-Na) as the template, 1-vinyl imidazole(VIZ) and vinyl acetate (VA) as monomer, and N, N-methylene bis acrylamide (MBAA) as cross-linkers and benzoyl peroxide as the initiator, two MIPs were prepared. In the preparation of non-impressed polymers (NIPs), the same composition was used without the template of amoxicillin sodium. Numerous plasticizers, such as tri-oly phosphate (TOP) and di-octyl phthalate (DOP), were used in the PVC matrix for the preparation of membranes. Slop, detection limit, lifetime, and linearity range of AMX-MIPs electrodes are the characteristics studied. There’s no interaction with the drug Amoxicillin sodium in the results obtained from selectivity measurements on interfering cations (K+, Ca+2, Al+3) and certain pharmaceutical additives such as methylparaben propylparaben and trisodium citrate. The preparation electrodes have been shown good response, including testing pharmaceutical analysis. © 2021, Dr. Yashwant Research Labs Pvt. Ltd. All rights reserved. 
(MBAA) Cross-linkers; Amoxicillin sodium; Different plasticizers; Molecularly imprinted polymers; Potentiometric method; acetic acid; amoxicillin; benzoyl peroxide; citrate trisodium; methyl paraben; molecularly imprinted polymer; monomer; n,n' methylenebisacrylamide; phenylephrine; phthalic acid dioctyl ester; plasticizer; polymer; polyvinylchloride; propyl paraben; sodium; vinyl acetate; Article; cross linking; drug solubility; drug synthesis; measurement precision; nonhuman; particle size; pH; pharmaceutics; physical chemistry; polymerization; scanning electron microscopy; viscosity; voltammetry