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HERO ID
9664955
Reference Type
Journal Article
Title
Endocrine disease in pregnancy
Author(s)
Frise, CJ; Williamson, C
Year
2013
Is Peer Reviewed?
1
Journal
Clinical medicine: Journal of the Royal College of Physicians of London
ISSN:
1470-2118
EISSN:
1473-4893
Volume
13
Issue
2
Page Numbers
176-181
Language
English
PMID
23681868
DOI
10.7861/clinmedicine.13-2-176
Abstract
Endocrine disease is common in pregnancy. Most pre-existing endocrine conditions, if well controlled, have little impact on maternal or fetal morbidity. Uncontrolled endocrine conditions in pregnancy, whether poorly controlled pre-conception or newly diagnosed, are associated with a variety of adverse fetal outcomes and maternal morbidity. Also, transplacental transfer of maternal antibodies can have adverse fetal or neonatal consequences. The initial diagnosis of many conditions is hindered by the overlap of symptoms that occur in normal pregnancy and those that suggest specific endocrine pathologies, and also by the changes in reference ranges for common biochemical measurements that occur as a result of physiological changes in pregnancy. This article summarises the common endocrine disorders in pregnancy and describes how pregnancy can alter their investigation, treatment and ongoing management, as well as the potential effects on the fetus.
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