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HERO ID
9798966
Reference Type
Journal Article
Title
Coexistence of papillary thyroid cancer with Hashimoto thyroiditis
Author(s)
Konturek, A; Barczyński, M; Wierzchowski, W; Stopa, M; Nowak, W
Year
2013
Is Peer Reviewed?
1
Journal
Langenbeck's Archives of Surgery
ISSN:
1435-2443
EISSN:
1435-2451
Volume
398
Issue
3
Page Numbers
389-394
Language
English
PMID
23099542
DOI
10.1007/s00423-012-1021-x
Abstract
AIMS:
Conflicting data have been reported with regard to Hashimoto thyroiditis (HT) and risk of malignancy. The aim of this study was to evaluate coexistence of papillary thyroid cancer (PTC) with HT.
PATIENTS AND METHODS:
This is a retrospective cohort study in which HT was diagnosed in 452 (F/M ratio = 405:47, median age 53.5 ± 12.1 years) of 7,545 patients qualified for thyroidectomy throughout the years 2002 to 2010. Pathological reports were reviewed to identify prevalence of PTC in HT vs. non-HT patients.
RESULTS:
PTC was diagnosed in 106 of 452 (23.5 %) HT patients vs. 530 of 7,093 (7.5 %) non-HT patients (p < 0.001). Metastases to level VI lymph nodes were observed in 81 of 106 (76.4 %) patients with PTC in HT vs. 121 of 530 (22.8 %) patients with PTC in non-HT disease (p < 0.001).
CONCLUSIONS:
HT was associated with a threefold increase of PTC prevalence as compared to other non-HT thyroid diseases, and the spread of PTC to level VI lymph nodes was four times more frequent in HT than in non-HT patients.
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