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982867 
Journal Article 
Review 
Pomegranate juice: a heart-healthy fruit juice 
Basu, A; Penugonda, K 
2009 
1 
Nutrition Reviews
ISSN: 0029-6643
EISSN: 1753-4887 
67 
1 
49-56 
English 
19146506 
WOS:000261881200006 
Pomegranate juice is a polyphenol-rich fruit juice with high antioxidant capacity. In limited studies in human and murine models, pomegranate juice has been shown to exert significant antiatherogenic, antioxidant, antihypertensive, and anti-inflammatory effects. Pomegranate juice significantly reduced atherosclerotic lesion areas in immune-deficient mice and intima media thickness in cardiac patients on medications. It also decreased lipid peroxidation in patients with type 2 diabetes, and systolic blood pressure and serum angiotensin converting enzyme activity in hypertensive patients. Thus, the potential cardioprotective benefits of pomegranate juice deserve further clinical investigation, and evidence to date suggests it may be prudent to include this fruit juice in a heart-healthy diet. 
antioxidants; atherosclerosis; ellagic acid; hypertension; pomegranates