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HERO ID
9906651
Reference Type
Journal Article
Subtype
Review
Title
The contribution of the sodium-calcium exchanger (NCX) and plasma membrane Ca(2+) ATPase (PMCA) to cerebellar synapse function
Author(s)
Roome, CJ; Empson, RM
Year
2013
Is Peer Reviewed?
Yes
Journal
Advances in Experimental Medicine and Biology
ISSN:
0065-2598
Volume
961
Page Numbers
251-263
Language
English
PMID
23224885
DOI
10.1007/978-1-4614-4756-6_21
Abstract
The cerebellum, a part of the brain critically involved in motor learning and sensory adaptation, expresses high levels of the sodium-calcium exchanger (NCX) and the plasma membrane calcium ATPase (PMCA). Both these transporters control calcium dynamics at a variety of synapses, and here, we draw upon the available literature to discuss how NCX and PMCA work together to shape pre-synaptic calcium dynamics at cerebellar synapses.
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