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9914282 
Journal Article 
[Hypothyroidism as the result of drug interaction between ferrous sulfate and levothyroxine] 
Fiaux, E; Kadri, K; Levasseur, C; Le Guillou, C; Chassagne, P 
2010 
1 
La Revue de Médecine Interne
ISSN: 0248-8663 
31 
10 
e4-e5 
French 
20554088 
We report a case of drug-drug interaction between ferrous sulfate and l-thyroxin. A 95-year-old woman treated successfully with l-thyroxin for many years received ferrous sulfate for anemia. This association led rapidly to recurrence of hypothyroidism with elevated serum than TSH level which completely resolved after withdrawal of iron therapy. Interaction was confirmed after both drugs were daily administrated separately without recurrence of hypothyroidism.