Heavy metal chelation in neurotoxic exposures | Health & Environmental Research Online (HERO)

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Citation
Tags

HERO ID

1021610

Reference Type

Journal Article

Subtype

Review

Title

Heavy metal chelation in neurotoxic exposures

Author(s)

Jang, DH; Hoffman, RS

Year

2011

Is Peer Reviewed?

Journal

Neurologic Clinics
ISSN: 0733-8619
EISSN: 1557-9875

Volume

Issue

Page Numbers

607-622

Language

English

PMID

21803213

DOI

10.1016/j.ncl.2011.05.002

Web of Science Id

WOS:000294373800006

Abstract

Metals such as iron and copper are critical to living organisms, whereas other metals such as lead and arsenic have no known biologic role. Any metals in large amounts may cause toxicity. Many metals cause pervasive systemic effects involving the nervous system, which can be subtle in some cases. Although challenging, the diagnosis and treatment of metal poisoning can be made based on history, physical examination, and the proper use of metal testing. This article focuses on the use, and misuse, of chelation in the diagnosis and management of metal intoxication.

Keywords

Heavy metals; Chelation; Postchelation challenge; Neurotoxic