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1034165 
Journal Article 
Rapid, sensitive method for the separation and detection of arsenic compounds in biological systems 
Edwards, T; Merilees, HL; Mcbride, BC 
1975 
Yes 
Journal of Chromatography A
ISSN: 0021-9673
EISSN: 1873-3778 
PESTAB/75/2046 
106 
210-212 
English 
239011 
PESTAB. A simple, rapid, one-step procedure for identifying arsenic compounds in complex biological systems has been developed. Samples of distilled water or domestic sewage sludge containing sodium arsenate, sodium arsenite, sodium methyl arsonate, or sodium cacodylate were prepared. The samples were centrifuged and the supernatants analyzed by electrophoresis on nonfluorescent cellulose thin-layer chromatographic sheets. At pH 7.0, arsenate, methylarsonate, and cacodylate migrated to the anode; arsenite moved to the cathode. Assigning arsenate a mobility of 1.0, methylarsonate and cacodylate had relative mobilities of 0.86 and 0.47, respectively. In addition, methylarsonate appeared as a light blue spot, while arsenate was dark blue. Sodium tellurate, sodium nitrate, sodium nitrate, sodium sulfite, and sodium sulfate did not interfere with migration or form colored complexes with the developing reagents. Sodium phosphate appeared as a blue spot with a relative mobility of 0.84. Large quantities of contaminating salt, protein, lipid, and carbohydrate had no adverse effects on the system. 
IRIS
• Arsenic (Inorganic)
     1. Literature
          PubMed
          Toxline, TSCATS, & DART
• Inorganic Arsenic (7440-38-2) [Final 2025]
     1. Initial Lit Search
          PubMed
          ToxNet
     4. Considered through Oct 2015
     6. Cluster Filter through Oct 2015