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1044967 
Journal Article 
Carbohydrate metabolism genes and pathways in insects: insights from the honey bee genome 
Kunieda, T; Fujiyuki, T; Kucharski, R; Foret, S; Ament, SA; Toth, AL; Ohashi, K; Takeuchi, H; Kamikouchi, A; Kage, E; Morioka, M; Beye, M; Kubo, T; Robinson, GE; Maleszka, R 
2006 
Yes 
Insect Molecular Biology
ISSN: 0962-1075
EISSN: 1365-2583 
15 
5 
563-576 
English 
17069632 
WOS:000241625100005 
Carbohydrate-metabolizing enzymes may have particularly interesting roles in the honey bee, Apis mellifera, because this social insect has an extremely carbohydrate-rich diet, and nutrition plays important roles in caste determination and socially mediated behavioural plasticity. We annotated a total of 174 genes encoding carbohydrate-metabolizing enzymes and 28 genes encoding lipid-metabolizing enzymes, based on orthology to their counterparts in the fly, Drosophila melanogaster, and the mosquito, Anopheles gambiae. We found that the number of genes for carbohydrate metabolism appears to be more evolutionarily labile than for lipid metabolism. In particular, we identified striking changes in gene number or genomic organization for genes encoding glycolytic enzymes, cellulase, glucose oxidase and glucose dehydrogenases, glucose-methanol-choline (GMC) oxidoreductases, fucosyltransferases, and lysozymes. 
insect metabolome; lipid metabolism; cellulose degradation; gene synteny 
IRIS
• Methanol (Non-Cancer)
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