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1057366 
Journal Article 
Determination of Phthalate Esters in the Atmosphere by LC/MS/MS 
Hasegawa, A 
2003 
1 
Bunseki Kagaku / Analysis Chemistry
ISSN: 0525-1931 
JAPAN SOC ANALYTICAL CHEMISTRY 
TOKYO 
52 
1 
15-20 
Japanese 
WOS:000180542100002 
A analytical method was developed for the determination of phthalate ester plasticizers {diisononylphthalate (DINP), diisodecylphthalate (DIDP) and diisotridecylphthalate (DITP)} in the atmosphere by liquid-chromatography/ tandem mass spectrometry (LC/MS/MS). The ionization mode was positive-APCI (atmospheric pressure chemical ionization) and [M + H](+) ions were formed, which then fragmented by collosion with nitrogen. Sample air was drawn for 24 h at a constant flow rate (12 - 14 l/min) through a quartz fiber filter. After the collected substances were extracted into acetonitrile, di-(2-ethylhexyl)phthalate-d(4) (DEHP-d(4)) was added as an internal standard. The recoveries, relative standard deviation (RSD) and limit of detection (LOD) were 94 similar to 102%, 4.3 similar to 8.7% and 0.05 similar to 0.8 ng/m(3), respectively. DINP and DIDP were detected in outdoor and indoor air samples, including clean room air; concentrations were 1.2 similar to 9.6 and 0.1 similar to 1.4 ng/m(3), respectively. Because these phthalate esters are semi-volatile and include a mixture of many isomers, it is hard to obtain high analytical accuracy and precision by gaschromatograhy. The present method could be used to determine DINP and DIDP in air with high sensitivity. 
diisononylphthalate; diisodecylphthalate; diisotridecylphthalate; LC/MS/MS; air pollution 
IRIS
• Diisononyl Phthalate (DINP)
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