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HERO ID
1108426
Reference Type
Journal Article
Title
Phytochemical Assessment and Antioxidant Activities of Alcoholic and Aqueous Extracts of Acacia mearnsii De Wild
Author(s)
Olajuyigbe, OO; Afolayan, AJ
Year
2011
Is Peer Reviewed?
Yes
Journal
International Journal of Pharmacology
ISSN:
1811-7775
Volume
7
Issue
8
Page Numbers
856-861
Language
English
DOI
10.3923/ijp.2011.856.861
Web of Science Id
WOS:000298942600009
Abstract
Phenolic compounds are well known for their antioxidant activities. The objectives of this study were to determine the phenolic content of the crude extracts of Acacia mearnsii De Wild and to evaluate the antioxidant properties of these extracts. The Folin-ciocalteu procedure was used to assess the total phenolic compositions of the extracts as garlic acid equivalents. Antioxidant activity was evaluated using 2,2-Azinobis-3-ethyl benzothiazoline-6-sulfonic acid (ABTS) diammonium salt and l,l-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging methods. All the extracts showed antioxidant potential. Ethanolic extract had the highest total flavonoids. Acetone extract had the highest total phenolic contents. The total proanthocyanidins was highest in the methanol extract while aqueous extracts had the least of these phytochemicals. The reducing power of the extracts of A. mearnsii was dose dependent. Aqueous extract showed the least reducing power, methanol extract indicated the highest reducing power. The reducing power of the extracts is lower than those obtained from the reference standard such as Butylated Hydroxytoluene (BHT), Rutin and ascorbic acid. 2,2-Azinobis-3-ethyl Benzothiazoline-6-Sulfonic acid (ABTS) diammonium salt showed that ethanol extract exhibited the highest activity at the highest concentration tested. l,l-diphenyl-2-picrylhydrazyl (DPPH) assay indicated that ethanol extract had the highest activity at the lowest concentration and the activities of all the extracts decreased with increase in their concentrations. This study revealed a positive linear correlation between the total phenolic content and antioxidant activity of the extracts of A. mearnsii. © 2011 Asian Network for Scientific Information.
Keywords
Antioxidant activity; Acacia mearnsii extracts 2,2-azinobis-3-ethyl benzothiazoline-6-sulfonic acid; radical scavenging; reducing power
Tags
IRIS
•
Methanol (Non-Cancer)
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