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1131777 
Journal Article 
Metabolite analysis in Curcuma domestica using various GC-MS and LC-MS separation and detection techniques 
Herebian, D; Choi, JH; El-Aty, AMA; Shim, JH; Spiteller, M 
2009 
Yes 
Biomedical Chromatography
ISSN: 0269-3879
EISSN: 1099-0801 
WILEY 
HOBOKEN 
23 
9 
951-965 
English 
19358151 
WOS:000269227000007 
The metabolic profile of polar (methanol) and non-polar (hexane) extracts of Curcuma domestica, a widely used medicinal plant, was established using various different analytical techniques, including GC-FID, GC-MS, HR-GC-MS and analytical HPLC-ESI-MS/MS by means of LTQ-Orbitrap technology. The major non-volatile curcuminoids curcumin, demethoxycurcumin and bisdemethoxycurcumin were identified when their chromatographic and precursor ion masses were compared with those of authentic standard compounds. In this paper we describe for the first time a GC/MS-based method for metabolic profiling of the hydrophilic extract. We also identified 61 polar metabolites as TMS derivatives. 
Curcuma domestica; LTQ-Orbitrap; metabolite profile; (HR)-GC-MS; HPLC-ESI-MS/MS 
IRIS
• Methanol (Non-Cancer)
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