Synthesis, characterization and investigation of antioxidant activity of cobalt-quercetin complex | Health & Environmental Research Online (HERO)

Health & Environmental Research Online (HERO)

Print Feedback Export to File

This record has one attached file:

Citation
Tags

HERO ID

1133936

Reference Type

Journal Article

Title

Synthesis, characterization and investigation of antioxidant activity of cobalt-quercetin complex

Author(s)

Bukhari, SB; Memon, S; Tahir, MM; Bhanger, MI

Year

2008

Is Peer Reviewed?

Journal

Journal of Molecular Structure: Theochem
ISSN: 0166-1280
EISSN: 1872-7999

Volume

892

Issue

1-3

Page Numbers

39-46

DOI

10.1016/j.molstruc.2008.04.050

Web of Science Id

WOS:000261711400007

Abstract

This article describes a novel synthesis of cobalt and quercetin center dot 2H(2)O complex in methanol, characterized by using elemental analysis, UV-visible, (1)H NMR, TGA, DSC and IR spectrometric techniques. The formation of complex is deduced from the UV-visible spectra which shows that the successive formation of cobalt-quercetin complex occurs in a ratio of 2:1 (metal/ligand) stoichiometrically. The antioxidant activity of the complex was evaluated by using 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging method. In this work, we have shown that the metal complexed flavonoids are much more effective free radical scavengers than the free flavonoids. (C) 2008 Elsevier B.V. All rights reserved.

Keywords

Flavonoids; Antioxidant; Quercetin; Stoichiometry; Co(II) complexation; Spectroscopy