US EPA

1144160 

Journal Article 

Extraction and antimicrobial activity of mangosteen extract 

Sukatta, U; Dilokkunanant, U; Rugthaworn, P; Siriwan, S; Pitpiangchan, P; Kasetsart Univ 

2006 

KASETSART UNIV 

BANGKOK 

529-536 

WOS:000237173400071 

A study on extraction of mangosteen peel (Garcinia mangostana Linn.) by maceration and soxhlet extraction methods with ethanol and continuous extraction with hexane, acetone and methanol showed that the highest yield of crude extract about 26-59 % was obtained from dried peel cold extraction with ethanol. Sixteen crude extracts were investigated for their inhibitory effect against 5 microorganisms; Staphylococcus aureus, S. epidermidis, Propionibacterium acnes, Candida albicans and Trichophyton mentagrophytes, by disc diffusion method. The result showed that crude extract from fresh peel cold extraction with ethanol was the most effective in inhibiting growth of S. aureus, S. epidermidis, P. acnes and T. mentagrophytes. Mangosteen crude extract could not inhibit growth of C.albicans. Agar dilution method was used to determine Minimal Inhibitory Concentration (MIC) of fresh peel cold extraction. S. aureus was the most sensitive with MIC 128 mu g/ml, followed by P. acnes, 256 mu g/ml, S. epidermidis, 4096 mu g/ml, and T. mentagrophytes 8192 mu g/ml respectively. 

mangosteen; crude extract; inhibition efficacy; antimicrobial 

974-537-823-2 

44th Kasetsart-University Annual Conference 

Bangkok, THAILAND