Methoxycarbonylation versus hydroacylation of ethene; Dramatic influence of the ligand in cationic palladium catalysis | Health & Environmental Research Online (HERO)

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Citation
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HERO ID

1160654

Reference Type

Journal Article

Title

Methoxycarbonylation versus hydroacylation of ethene; Dramatic influence of the ligand in cationic palladium catalysis

Author(s)

Pugh, RI; Drent, E

Year

2002

Is Peer Reviewed?

Journal

Advanced Synthesis & Catalysis
ISSN: 1615-4150
EISSN: 1615-4169

Volume

344

Issue

Page Numbers

837-840

DOI

10.1002/1615-4169(200209)344:8<837::AID-ADSC837>3.0.CO;2-1

Web of Science Id

WOS:000178569400003

Abstract

The palladium-catalysed carbonylation of ethene in methanol shows acute sensitivity towards the diphosphine ligand used. Systems based on 1,3-bis(di-t-butylphosphino)propane afford catalysts for fast, selective methoxycarbonylation to methyl propionate; the corresponding catalyst based on 1,2-bis(di-t-butylphosphino)ethane hydroacylates ethene to diethyl ketone at high rates. The use of less sterically demanding ligands, hydrogen and auxiliary acid are explored and mechanistic implications discussed.

Keywords

alkenes; carbonylation; esters; ketones; palladium; P ligand