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1205433 
Journal Article 
REGIOSELECTIVE MONOMETHYLATION OF UNSYMMETRICAL NAPHTHALENEDIOLS WITH METHANOLIC HCL 
Bell, KH; Mccaffery, LF 
1993 
Yes 
Australian Journal of Chemistry
ISSN: 0004-9425
EISSN: 1445-0038 
46 
5 
731-737 
English 
WOS:A1993LD76900014 
Treatment of naphthalene-1, 3-diol and naphthalene-1, 7-diol with methanol containing dry hydrogen chloride at room temperature gives exclusively 3-methoxy-1-naphthol and 7-methoxy- 1-naphthol, respectively. Of the other two unsymmetrical naphthalenediols, the 1, 2-isomer was unreactive and the 1, 6-isomer gave a mixture of regioisomers under the same conditions. Two symmetrical diols (the 1, 5- and 2, 7-isomers) examined by the same procedure gave the monomethyl ethers in 60-70% yields. © 1993 ASEG. 
IRIS
• Methanol (Non-Cancer)
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