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1233816 
Journal Article 
Hexavalent chromium-induced congenital abnormalities in chick embryos 
Asmatullah; Qureshi, SN; Shakoori, AR 
1998 
Yes 
Journal of Applied Toxicology
ISSN: 0260-437X
EISSN: 1099-1263 
BIOSIS/98/25956 
18 
3 
167-171 
English 
9685044 
The embryotoxic and teratogenic potential of hexavalent chromium was evaluated in chick embryos. Different concentrations of aqueous solution of potassium dichromate ranging from 1.00 to 100.00 microg per egg were injected into chick eggs before incubation. A dose-dependent embryonic mortality was observed in all the groups examined on days 7 and 14 of incubation. The following malformations were observed in survivors: reduced body size and organs; microphthalmia; micromelia; everted viscera; abnormal and twisted neck, beak and spinal cord; isolated epicarditis; club foot; haemorrhage; and patchy feathers. Total mortality showing embryonic resorption was noted in higher dose groups (25-100 microg per egg) on day 14 of incubation. 
Genetics and Cytogenetics-Animal; Biochemical Studies-General; Toxicology-General; Galliformes 
IRIS
• Chromium VI
     Considered
          Potentially Relevant Supplemental Material
               Mechanistic