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1234604 
Journal Article 
Tylosin, an airborne contact allergen in veterinarians 
Caraffini, S; Assalve, D; Stingeni, L; Lisi, P 
1994 
Yes 
Contact Dermatitis
ISSN: 0105-1873
EISSN: 1600-0536 
NIOSH/00223574 
31 
5 
327-328 
English 
7867337 
A case study of a 31 year old man who had worked on a pig farm for 7 years and who recently developed erythema and itchy papules on the forehead, upper cheeks, and forearms was described. The lesions developed one day after administering the antibiotic Vetil. The antibiotic contains tylosin (1401690) in propylene-glycol (57556) and benzyl-alcohol (100516). The patient was patch tested and was positive to potassium-dichromate (7778509), undiluted Vetil solution, Vetil solution diluted 50%, and tylosin-tartrate (1405545). Once exposure to tylosin was stopped, the dermatitis cleared and there was no relapse since tylosin was replaced with aminoglycosides. The authors proposed that the location of the allergic dermatitis on the face of the patient suggested that there was airborne contact, possibly when the animals moved or when mixing tylosin powder with the feed. 
DCN-223109; Contact dermatitis; Occupational exposure; Skin disorders; Skin irritants; Humans; Veterinarians; Skin exposure; Case studies; Allergic dermatitis; Allergic reactions; Skin tests 
IRIS
• Chromium VI
     Considered
          Potentially Relevant Supplemental Material
               Human Case Reports