Strontium Chromate
Anonymous
| HERO ID | 1238487 |
|---|---|
| Year | 2001 |
| Title | Strontium Chromate |
| Authors | Anonymous |
| Volume | Documentation of the threshold limit values and biological exposure indices Vol |
| Abstract | A TLV-TWA of 0.0005 mg/m3, measured as chromium (Cr), is recommended for occupational exposure to strontium chromate. No published epidemiological or clinical studies of workers exposed to strontium chromate were identified in the open scientific or medical literature. However, long-term oncogenic studies with rodents resulted in statistically significant numbers of implantation-site tumors, including up to a 62% incidence of bronchial carcinomas compared with 0% in pellet-vehicle control animals. Furthermore, strontium chromate is of greater potency for tumorigenesis when compared to the reference carcinogens calcium chromate and methylcholanthrene. For these reasons, an A2, Suspected Human Carcinogen, notation is justified. In addition, for A2 carcinogens with a TLV, worker exposure by all routes should be carefully controlled to levels as low as possible below the TLV. Sufficient data were not available to recommend Skin or SEN notations or a TLV-STEL. |
| Report Number | RISKLINE/2003060041 |
| Is Certified Translation | No |
| Dupe Override | No |
| Comments | Journal: ACGIH ISSN: |
| Is Public | Yes |
| Language Text | English |
| Keyword | <?xml version="1.0" encoding="UTF-8"?><kw>ANIMAL</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>acute toxicity</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>carcinogenicity</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>carcinogens</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>mammary gland</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>nervous system</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>respiratory system</kw>; <?xml version="1.0" encoding="UTF-8"?><kw>HUMAN</kw> |
| Is Qa | No |