Health Risk Assessment of Embedded Depleted Uranium: Behavior, Physiology, Histology and Biokenetic Modeling | Health & Environmental Research Online (HERO)

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Citation
Tags

HERO ID

1424762

Reference Type

Technical Report

Title

Health Risk Assessment of Embedded Depleted Uranium: Behavior, Physiology, Histology and Biokenetic Modeling

Author(s)

Pellmar, TC

Year

1996

Report Number

NTIS/02933589_a

Volume

GRA and I

Issue

GRA and I

Abstract

This study evaluates the consequences of both short-term and long- term exposure to DU fragments in the rat model. Using an interdisciplinary approach, we are assessing neurotoxicity, nephro-toxicity, histopathology of the tissue surrounding the fragment and pathology including evaluation of neoplastic changes in several body tissues. In addition, based on our animal data, we will develop a biokinetic model that describes the distribution of uranium from embedded fragments as a function of time.

Keywords

Physiology; *Depleted uranium; *Histology; Tissues(Biology); Risk; Health; Toxicity; Neoplasms; Embedding; Nervous system; Animals; Human body; Pathology; Muscles; Rodents; Surgical implantation; Anatomical models; Biokenetic modeling; Intramuscular implants