US EPA

1579818 

Journal Article 

A Sampling and Analytical Method for Methyl Ethyl Ketone Peroxide 

Chan, Y; Schultz, GR; Shulsky, ML 

1991 

Yes 

Applied Occupational and Environmental Hygiene
ISSN: 1047-322X
EISSN: 1521-0898 

NIOSH/00199683 

6 

4 

309-314 

An improved sampling and analytical method was developed for monitoring occupational exposure to methyl-ethyl-ketone-peroxide (1338234) (MEKP). The method provided a determination that was specific for the two major components of MEKP found in commercial formulations. A commercial MEKP formulation was used to prepare analytical standards. Fifteen minute air samples were collected at 1 liter per minute with adsorbent tubes containing XAD-4 resins. Samples were stable for 15 days when stored at minus 25 degrees-C. 2-Propanol was used to extract the samples which were analyzed by normal phase high performance liquid chromatography. The resolved monomer and dimer were subjected to a post column reaction that resulted in the production of quantitative amounts of iodine, quantitated with an ultraviolet detector. The authors recommend this method for monitoring workplace exposure to MEKP because it is specific, allows the use of adsorbent tube samplers, and is based on the characteristics of MEKP found in the workplace. 

DCN-195130; Analytical methods; Analytical chemistry; Chemical analysis; Chromatographic analysis; Ketones; Peroxides; Plastics industry