Health & Environmental Research Online (HERO)


Print Feedback Export to File
1854752 
Journal Article 
Terbinafine-induced fixed drug eruption with the characteristic distribution of "Baboon-Syndrome" 
Weiss, JM; Mockenhaupt, M; Schopf, E; Simon, JC 
2001 
Yes 
Der Hautarzt
ISSN: 0017-8470
EISSN: 1432-1173 
52 
12 
1104-1106 
German 
11910862 
WOS:000173039500007 
A 26 year old patient developed a fixed drug eruption located on his hands, inguinal and gluteal areas following oral treatment of onychomycosis with terbinafine. The rash showed the characteristic distribution of the "baboon-syndrome", so-named because of the red perianal region of the baboon. Although epicutaneous testing revealed no positive reaction, the rash could be induced in identical sites by oral administration of terbinafine. As the underlying pathomechanism for the "baboon-syndrome" a systemically induced allergic contact dermatitis has been suggested. In addition to the described substances, e.g. mercury, amoxicillin, ampicillin, heparin and nickel, this is the first report of "baboon syndrome" induced by terbinafine. 
baboon syndrome; fixed drug eruption; terbinafine 
IRIS
• Methylmercury
     ADME Search: Jan 1990 - Nov 2018
          Results with mercury
               PubMed
               WoS