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1858037 
Journal Article 
Role of ear piercing in metal allergic contact dermatitis 
Nakada, T; Iijima, M; Nakayama, H; Maibach, HI 
1997 
Yes 
Contact Dermatitis
ISSN: 0105-1873
EISSN: 1600-0536 
BIOSIS/97/18072 
36 
5 
233-236 
English 
9197955 
WOS:A1997XC36000001 
BIOSIS COPYRIGHT: BIOL ABS. To evaluate the effect of ear piercing on sensitization to gold and other metals, diagnostic patch testing with 18 metals was performed. 377 patients (65 men and 312 women, ranging in age from 15 to 78 years; mean 34.2, S.D|15.1 years) were patch tested; 107 had pierced earlobes. Metals were applied on the back for 2 days, and the results read with the ICDRG scoring system 3 days after application. Reactions of + to +++ were regarded as positive. There were significantly more patients reacting to gold chloride (p<0.001), mercuric chloride (p<0.01), and nickel sulfate (p<0.05) in patients with pierced ears than in those without. Statistical issues included: (i) a significant number of patients with pierced ears referred because of earring dermatitis; (ii) those with pierced ears represented a different age group from those without; (iii) a significant number of patients without eczema in the non-pierced ear group. However, our data suggests that ear piercing is 
ear piercing; allergic contact dermatitis; false-positive reactions; patch testing technique; gold chloride; mercuric chloride; nickel sulfate; product labelling 
• Inorganic Mercury Salts (2)
     Mercuric Chloride
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     Mercurous Chloride
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