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2078952 
Technical Report 
The acute toxicity of the hydrolysis products of uranium hexafluoride (UF6) when inhaled by the rat and guinea pig. Final report 
Leach, L. J.; Gelein, R. M. ; Panner, B. J.; et al 
1984 
Yes 
ISS K/SUB-81-9039-3. DE84011539 
English 
This report presents the experimental animal data base from which human health consequences may be predicted from exposures mimicing accidental discharges of uranium hexafluoride (UF sub 6 ) in the uranium industry. Rats or guinea pigs were exposed for two, five, or ten minutes duration to air having 0.44 g U/m exp 3 + 0.16 g HF/m exp 3 to 276.67 g U/m exp 3 + 94.07 g HF/m exp 3 . Survivors of each exposure were observed for 14 days for signs of U or HF intoxication. Selected animals were necropsied and samples of major organs were studied histopathologically. When enriched UF sub 6 (94 percent exp 235 U) was used, the urine and feces from each animal were measured daily for U content. Selected samples of urine were bioassayed in order to trace the course of renal injury during the two week postexposure period. 28 references, 51 figures, 23 tables. (ERA citation 09:031808) 
DE84011539