US EPA

2248008 

Journal Article 

Computed tomography features of liparitosis: a pneumoconiosis due to amorphous silica 

Mazziotti, S; Gaeta, M; Costa, C; Ascenti, G; Barbaro Martino, L; Spatari, G; Settineri, N; Barbaro, M 

2004 

Yes 

European Respiratory Journal
ISSN: 0903-1936
EISSN: 1399-3003 

23 

2 

208-213 

English 

14979493 

10.1183/09031936.04.00028904 

WOS:000188868700008 

The purpose of this study was to describe the radiological features of pleural, parenchymal and mediastinal damage due to occupational inhalation of pumice. In total, 31 workers were evaluated for annual follow-up. Spiral computed tomography (CT) was obtained in the three patients with evident parenchymal abnormalities at chest radiograph. High-resolution computed tomography (HRCT) was performed in the remaining 28 subjects with no radiographical evidence of pleuropulmonary damage or evidence of pleural plaques, in order to exclude parenchymal involvement. Pumice samples were analysed by radiograph diffraction and scanning electron microscopy. Spiral CT showed parahilar conglomerate masses containing fine reticular calcifications in three of 31 (9.7%) patients. HRCT showed several bilateral pleural plaques, without any parenchymal lesion in eight of 28 (28.6%) cases. Statistical analysis indicated correlation between CT findings and pulmonary function, as well as exposure to pumice. The analysis of pumice excluded the presence of asbestos. The findings from this study suggest that pleural plaque may be the only sign of disease in patients with a history of pumice inhalation. However, conglomerate parahilar masses are probably due to exposure to massive amounts of heated pumice, and seem to have different pathogenesis and histopathological characteristics to silicosis. 

amorphous silica; computed tomography; lung; pleura; pumice