US EPA

2745760 

Journal Article 

End stage renal disease among ceramic workers exposed to silica 

Rapiti, E; Sperati, A; Miceli, M; Forastiere, F; Di Lallo, D; Cavariani, F; Goldsmith, DF; Perucci, CA 

1999 

1 

Occupational and Environmental Medicine
ISSN: 1351-0711
EISSN: 1470-7926 

BIOSIS/99/23430 

56 

8 

559-561 

English 

10492655 

10.1136/oem.56.8.559 

WOS:000081701300010 

BIOSIS COPYRIGHT: BIOL ABS. Objectives To evaluate whether ceramic workers exposed to silica experience an excess of end stage renal disease. Methods On the basis of a health surveillance programme, a cohort of 2980 male ceramic workers has been enrolled during the period 1974-91 in Civitacastellana, Lazio, Italy. For each worker, employment history, smoking data, and x ray film readings were available. The vital status was ascertained for all cohort members. All 2820 people still alive and resident in the Lazio region as es was detected when 1.87 were expected (observed/expected (O)=3.21; 95% confidence interval (95% CI) 1.17 to 6.98). The excess risk was present among non-smokers (O=2; O/E=4.34) and smokers (O=4; O/E=2.83), as well as among workers without silicosis (O=4; O/E=2.78) and workers with silicosis (O=2; O/E=4.54). The risk was higher among subjects with and lt;20 years since first employment (O=4; O/E=4.65) than among those employed and gt;20 years. Conclusion These results provide further 

ceramics; end stage renal disease; silica; surveillance