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HERO ID
2745760
Reference Type
Journal Article
Title
End stage renal disease among ceramic workers exposed to silica
Author(s)
Rapiti, E; Sperati, A; Miceli, M; Forastiere, F; Di Lallo, D; Cavariani, F; Goldsmith, DF; Perucci, CA
Year
1999
Is Peer Reviewed?
1
Journal
Occupational and Environmental Medicine
ISSN:
1351-0711
EISSN:
1470-7926
Report Number
BIOSIS/99/23430
Volume
56
Issue
8
Page Numbers
559-561
Language
English
PMID
10492655
DOI
10.1136/oem.56.8.559
Web of Science Id
WOS:000081701300010
Abstract
BIOSIS COPYRIGHT: BIOL ABS. Objectives To evaluate whether ceramic workers exposed to silica experience an excess of end stage renal disease. Methods On the basis of a health surveillance programme, a cohort of 2980 male ceramic workers has been enrolled during the period 1974-91 in Civitacastellana, Lazio, Italy. For each worker, employment history, smoking data, and x ray film readings were available. The vital status was ascertained for all cohort members. All 2820 people still alive and resident in the Lazio region as es was detected when 1.87 were expected (observed/expected (O)=3.21; 95% confidence interval (95% CI) 1.17 to 6.98). The excess risk was present among non-smokers (O=2; O/E=4.34) and smokers (O=4; O/E=2.83), as well as among workers without silicosis (O=4; O/E=2.78) and workers with silicosis (O=2; O/E=4.54). The risk was higher among subjects with and lt;20 years since first employment (O=4; O/E=4.65) than among those employed and gt;20 years. Conclusion These results provide further
Keywords
ceramics; end stage renal disease; silica; surveillance
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