Health & Environmental Research Online (HERO)


Print Feedback Export to File
2820559 
Journal Article 
The Glycol Cleavage in Natural Product Synthesis: Reagent Classics and Recent Advances 
Schmidt, AKC; Stark, CBW 
2014 
1 
Synthesis
ISSN: 0039-7881
EISSN: 1437-210X 
46 
24 
3283-3308 
WOS:000345899300001 
This review focuses on the application of glycol cleavage reactions in the synthesis and derivatization of complex natural products. Reagent classics as well as recent developments are discussed. 1Introduction 2Mechanistic Aspects 3Reagents and Examples 3.1Periodate and Hypervalent Iodine 3.1.1Periodic Acid and Periodates 3.1.2Periodate on Wet Silica Gel 3.1.3Phenyliodine Diacetate 3.1.4Other Iodine Reagents 3.2Lead Tetraacetate 3.3Chromium Reagents 3.3.1Pyridinium Chlorochromate 3.3.2Other Chromium Reagents 3.4Ruthenium Reagents 3.4.1Tetra-n-propylammonium Perruthenate 3.4.2Other Ruthenium Reagents 3.5Manganese Reagents 3.5.1Manganese(III) Acetate 3.5.2Manganese Dioxide 3.5.3Other Manganese Reagents 3.6Miscellaneous 4Conclusion 
oxidation; diols; glycol cleavage; natural products; total synthesis 
IRIS
• Chromium VI
     Considered
          Excluded
               Other Not Pertinent
     Lit Search Updates
          February 2014 - December 2014