Jump to main content
US EPA
United States Environmental Protection Agency
Search
Search
Main menu
Environmental Topics
Laws & Regulations
About EPA
Health & Environmental Research Online (HERO)
Contact Us
Print
Feedback
Export to File
Search:
This record has one attached file:
Add More Files
Attach File(s):
Display Name for File*:
Save
Citation
Tags
HERO ID
3358697
Reference Type
Journal Article
Title
Time Course of Heart Rate Variability Response to PM2.5 Exposure from Secondhand Smoke
Author(s)
Garza, JL; Mittleman, MA; Zhang, J; Christiani, DC; Cavallari, JM
Year
2016
Is Peer Reviewed?
1
Journal
PLoS ONE
EISSN:
1932-6203
Volume
11
Issue
5
Page Numbers
e0154783
Language
English
PMID
27223894
DOI
10.1371/journal.pone.0154783
Web of Science Id
WOS:000376881700009
Abstract
PURPOSE:
Exposure to secondhand smoke (SHS) has been associated with decreased heart rate variability (HRV). However, the time course of this association is unclear. Therefore, the objective of this study was to investigate the association between 15-240 minute SHS-related fine particulate matter (PM2.5) moving averages and indices of HRV.
METHODS:
With a panel study design, we used personal monitors to continuously measure PM2.5 and HRV of 35 participants who were exposed to SHS for approximately 6 hours.
RESULTS:
We observed negative, significant associations between 5-minute HRV indices and 15 minute PM2.5 moving averages and 240 minute PM2.5 moving averages: there was a significant (p<0.01) 7.5% decrease in the 5-minute square root of the mean squared differences of successive normal heart beats associated with (RMSSD), and a significant (p<0.01) 14.7% decrease in the 5-minute high frequency (HF) power associated with the 15 minute PM2.5 moving averages; there was also a significant (p<0.01) 46.9% decrease in the 5-minute RMSSD, and a significant (p<0.01) 77.7% decrease in the 5-minute high frequency (HF) power associated with the 240 minute PM2.5 moving averages.
CONCLUSIONS:
Our findings that exposure to SHS related PM2.5 was associated with HRV support the hypothesis that SHS can affect the cardiovascular system. The negative associations reported between short and longer term PM2.5 and HRV indicate adverse effects of SHS on the cardiovascular system.
Tags
NAAQS
•
ISA-PM (2019)
Considered
In Scope
Mode of action
•
LitSearch-NOx (2024)
Forward Citation Search
Epidemiology
Results
Cardiovascular-ST
PubMed
WoS
Home
Learn about HERO
Using HERO
Search HERO
Projects in HERO
Risk Assessment
Transparency & Integrity