US EPA

3360718 

Journal Article 

Review 

Beyond PM2.5: The role of ultrafine particles on adverse health effects of air pollution 

Chen, R; Hu, B; Liu, Y; Xu, J; Yang, G; Xu, D; Chen, C 

2016 

1 

Biochimica et Biophysica Acta
ISSN: 0006-3002
EISSN: 1878-2434 

ELSEVIER 

AMSTERDAM 

1860 

12 

2844-2855 

English 

26993200 

10.1016/j.bbagen.2016.03.019 

WOS:000384866700009 

BACKGROUND: Air pollution constitutes the major threat to human health, whereas their adverse impacts and underlying mechanisms of different particular matters are not clearly defined.

SCOPE OF REVIEW: Ultrafine particles (UFPs) are high related to the anthropogenic emission sources, i.e. combustion engines and power plants. Their composition, source, typical characters, oxidative effects, potential exposure routes and health risks were thoroughly reviewed.

MAJOR CONCLUSIONS: UFPs play a major role in adverse impacts on human health and require further investigations in future toxicological research of air pollution.

GENERAL SIGNIFICANCE: Unlike PM2.5, UFPs may have much more impacts on human health considering loads of evidences emerging from particulate matters and nanotoxicology research fields. The knowledge of nanotoxicology contributes to the understanding of toxicity mechanisms of airborne UFPs in air pollution. This article is part of a Special Issue entitled Air Pollution, edited by Wenjun Ding, Andy Ghio and Weidong Wu.