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3393032 
Book/Book Chapter 
An evaluation and interpretation of reproductive endpoints for human health risk assessment 
Daston, GP; Kimmel, CA 
1998 
Yes 
ILSI Press 
Washington, DC 
An evaluation and interpretation of reproductive endpoints for human health risk assessment 
English 
has chapter(s) 3393147 Oocyte quantitation and ovarian histology
Methodologies to assess the potential of various chemical substances to produce reproductive and developmental toxicity are an important component of traditional toxicity testing for human health risk assessment. A number of new endpoints were proposed recently for incorporation into developmental and reproductive toxicity testing protocols with the goal of improving the ability and the sensitivity of test batteries to predict potential adverse effects in humans. Because of the general lack of experience in measuring and interpreting several of these nontraditional reproductive endpoints, the Developmental and Reproductive Toxicology Subcommittee of the International Life Sciences Institute (ILSI) Health and Environmental Sciences Institute (HESI) identified a need for the development of scientific consensus regarding the utility of these and other more commonly measured reproductive endpoints in characterizing a compound’s potential for reproductive toxicity, the interrelationship among endpoints, how the endpoints should be measured, and how the data from the studies should be interpreted for human health risk assessment. 
9781578810437 
Workshop on the Evaluation and Interpretation of Reproductive Endpoints for Human Health Risk Assessment 
Washington, DC 
1997 
PFAS
• PFHxS