US EPA

3402323 

Journal Article 

Review 

The Fundamental Role of NOX Family Proteins in Plant Immunity and Their Regulation 

Wang, YaJ; Wei, XY; Jing, X; Chang, Y; Hu, CH; Wang, X; Chen, K 

2016 

Yes 

International Journal of Molecular Sciences
ISSN: 1422-0067
EISSN: 14220067 

17 

6 

English 

27240354 

10.3390/ijms17060805 

WOS:000378799300019 

NADPH oxidases (NOXs), also known as respiratory burst oxidase homologs (RBOHs), are the major source of reactive oxygen species (ROS), and are involved in many important processes in plants such as regulation of acclimatory signaling and programmed cell death (PCD). Increasing evidence shows that NOXs play crucial roles in plant immunity and their functions in plant immune responses are not as separate individuals but with other signal molecules such as kinases, Rac/Rop small GTPases and hormones, mediating a series of signal transmissions. In a similar way, NOX-mediated signaling also participates in abiotic stress response of plants. We summarized here the complex role and regulation mechanism of NOXs in mediating plant immune response, and the viewpoint that abiotic stress response of plants may be a kind of special plant immunity is also proposed. 

NADPH oxidases; reactive oxygen species; kinases; Ca2+; hormones; abiotic stress; biotic stress