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3453366 
Journal Article 
Two new quinones from the roots of Juglans mandshurica 
Jin, M; Sun, J; Li, R; Diao, S; Zhang, C; Cui, J; Son, JK; Zhou, W; Li, G 
2016 
Yes 
Archives of Pharmacal Research
ISSN: 0253-6269
EISSN: 1976-3786 
39 
9 
1237-1241 
English 
27397432 
Two new quinones, 1-hydroxy-5-pentyl-anthraquinone (1) and 4-(5-hydroxy-1,4-dioxo-1,4-dihydro-naphthalen-2-ylamino)-butyric acid methyl ester (2), together with two known quinones, 5-hydroxy-2-(2-hydroxy-ethylamino)-(1,4) naphthoquinone (3) and juglone (4) were isolated from the roots of Juglans mandshurica (Juglandaceae). Their structures were elucidated on the basis of spectral data. Compound 3 was isolated from the Juglans genus for the first time. Compounds 1-4 exhibited significant cytotoxicity towards cultured MDA-MB231, HepG2 and SNU638 cells with IC50 values ranging from 4.46 to 88.47 μM.