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3537188 
Journal Article 
Biodiesel production using immobilized lipase: feasibility and challenges 
Sankaran, R; Show, PauL; Chang, JoShu 
2016 
Biofuels, Bioproducts and Biorefining
ISSN: 1932-104X 
10 
896-916 
Fatty acid alkyl esters (FAAE, also known as biodiesel) is
one of the best alternatives to fossil fuels. Biodiesel can be synthesized via
transesterification of oil with alcohol by either chemical or enzymatic catalysis. In particular,
immobilized lipase as biocatalyst for transesterification has recently drawn great attention due
to its environmental and economic benefits over conventional chemical catalytic processes. This
paper provides an in-depth review of the feasibility and the challenges of biodiesel production
catalyzed by immobilized lipase, with the emphasis on lipase immobilization techniques, factors
affecting biodiesel synthesis, and whole cell catalysis. It is necessary to upgrade the existing
methods and to further exploit new techniques to make the immobilized lipase-catalyzed biodiesel
synthesis technically feasible and commercially viable for practical applications. (c) 2016
Society of Chemical Industry and John Wiley & Sons, Ltd 
biodiesel; lipase; transesterification; enzyme immobilization; whole cell catalysis