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HERO ID
3699004
Reference Type
Journal Article
Title
Antimicrobial Potentials of Leptolyngbya sp. and Its Synergistic Effects With Antibiotics
Author(s)
Abazari, M; Zarrini, G; Rasooli, I
Year
2013
Is Peer Reviewed?
1
Journal
Jundishapur Journal of Microbiology
ISSN:
2008-3645
EISSN:
2008-4161
Volume
6
Issue
5
DOI
10.5812/jjm.6536
Web of Science Id
WOS:000324572600011
Abstract
Background: Resistance to antibiotics is a clinical problem. Cyanobacteria have many more antibiotic productions. Nowadays, combinations of antimicrobial compounds are used.
Objectives: The current research studied antimicrobial properties of Leptolyngbya sp.
Materials and Methods: Chloroform extracts of Leptolyngbya sp. were prepared. Antimicrobial effects of these extracts were evaluated singly and in combination with antibiotics against various microorganisms. Growth optimization, antimicrobial activity and their correlations were studied.
Results: Leptolyngbya sp. had antimicrobial activity individually and in synergy with antibiotics against Gram-positive and Gram-negative bacteria. The highest activity of the chloroform extract was on Gram positive strains and its effects on fungi were moderate, but it had a little effect against Gram negative ones. Phosphate salt was the most important factor for growth and antibacterial activity in C. leptolyngbya.
Conclusions: Optimization of medium composition and synergistic antimicrobial activity on the cyanobacteria could lead to production of effective antimicrobials.
Keywords
Cyanobacteria spp.; Leptolyngbya sp.; Synergism
Tags
•
Chloroform 2018 Update
TITLE AND ABSTRACT REVIEW
Excluded Studies
•
Chloroform Combined (current)
Chloroform (original)
References: 2000-2018
WoS
Chloroform (2018 update)
TITLE AND ABSTRACT REVIEW
Excluded Studies
Chloroform (current)
Literature Search: Jan 2009 - March 2017
Web of Science
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