US EPA

3799341 

Journal Article 

Haematological responses in a freshwater fish Channa punctatus (Bloch) exposed to profenofos 

Pandey, AK; Nagpure, NS; Trivedi, SP 

2011 

1 

National Academy Science Letters
ISSN: 0250-541X
EISSN: 2250-1754 

34 

9-10 

359-365 

WOS:000298314400009 

Toxicological investigations of organophosphate pesticide profenofos exposed to a freshwater fish, Channa punctatus by using haematological parameters. On the basis of calculated valves of LC(50) of profenofos in the fish 15 days laboratory acclimatized fishes were divided into three groups and exposed to three test concentrations of profenofos viz., sublethal-I (1/4th of LC(50)), sublethal-II (1/2nd of LC(50)) and sublethal-III (3/4th of LC(50)). The blood sampling was done at regular intervals of 24 h for assessment of heamatological indices. Some notable changes were recorded which include red blood cells (RBC) count, white blood cells (WBC) count, haemoglobin percentage and clotting time (CT). The significant decrease in RBC count, Hb %, and CT and increase in total leukocyte count is suggestive of noxious nature of the pesticide for the fish C. punctatus. The observed haematological responses may be used as non-specific biomarkers in the field of eco-toxicology. 

Toxicological; Channa punctatus; profenofos; haematological; eco-toxicology