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4244898 
Journal Article 
Review 
Neurodevelopment, GABA system dysfunction, and schizophrenia 
Schmidt, MJ; Mirnics, K 
2015 
1 
Neuropsychopharmacology
ISSN: 0893-133X
EISSN: 1740-634X 
40 
1 
190-206 
English 
24759129 
WOS:000346146400014 
The origins of schizophrenia have eluded clinicians and researchers since Kraepelin and Bleuler began documenting their findings. However, large clinical research efforts in recent decades have identified numerous genetic and environmental risk factors for schizophrenia. The combined data strongly support the neurodevelopmental hypothesis of schizophrenia and underscore the importance of the common converging effects of diverse insults. In this review, we discuss the evidence that genetic and environmental risk factors that predispose to schizophrenia disrupt the development and normal functioning of the GABAergic system. 
IRIS
• RDX (121-82-4)
     SAB 2017 references