Health & Environmental Research Online (HERO)


Print Feedback Export to File
4300430 
Journal Article 
Review 
ROS-mediated lipid peroxidation and RES-activated signaling 
Farmer, EE; Mueller, MJ 
2013 
Yes 
Annual Review of Plant Biology
ISSN: 1543-5008
EISSN: 1545-2123 
64 
429-450 
English 
23451784 
WOS:000321699500018 
Nonenzymatic lipid oxidation is usually viewed as deleterious. But if this is the case, then why does it occur so frequently in cells? Here we review the mechanisms of membrane peroxidation and examine the genesis of reactive electrophile species (RES). Recent evidence suggests that during stress, both lipid peroxidation and RES generation can benefit cells. New results from genetic approaches support a model in which entire membranes can act as supramolecular sinks for singlet oxygen, the predominant reactive oxygen species (ROS) in plastids. RES reprogram gene expression through a class II TGA transcription factor module as well as other, unknown signaling pathways. We propose a framework to explain how RES signaling promotes cell "REScue" by stimulating the expression of genes encoding detoxification functions, cell cycle regulators, and chaperones. The majority of the known biological activities of oxygenated lipids (oxylipins) in plants are mediated either by jasmonate perception or through RES signaling networks. 
NAAQS
• ISA-Ozone (2020 Final Project Page)
     Literature Search Results
     Literature Search - Included
          Citation Mapping
               Ecology
     Title-Abstract Screening (SWIFT-AS) - Excluded
          SWIFT-AS Excluded